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Steven Johnsons syndrome
Thursday, November 09, 2006




Steven Johnsons syndrome is an immune complex hypersensitivity disorder known to be caused by certain

  1. Antibiotics like cotrimoxazole and penicillin
  2. Viral infections, and bacterial infections like AIDS, and herpes
  3. Radiation theraphy for malignancies
  4. Antiretroviral therapy-Combivir & Nevirapine (NVP)
It is commonly found in young adults and children. Affected individuals usually present with flu-like manifestations like headache, fever, cough, and body aches. There is severe blistering of the skin and mucous membranes of the mouth, eyes, nose, vagina, urinary, respiratory, and digestive tracts.

It takes around several weeks before recovery sets in. The individual is treated with antibiotics for infection, analgesics, and steroids. Fluid consumption is also increased.

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posted by Rodolfo T. Rafael,M.D. @ 8:02 PM  
3 Comments:
  • At 10:01 PM, Blogger zandperl said…

    I'd like to see you highlight hidradenitis suppurativa some time. It's a skin condition where the apocrine sweat glands get clogged and have bacteria in them and the person's immune system overreacts and causes inflammations - sometimes the size of baseballs. It's a dehumanizing disease, but it's not well studied so the cause is still debated by doctors. Sometimes it's even misdiagnosed - apocrine sweat glands are found in the armpits, chest, and groin, so some doctors at first think it's an STD.

    Great site!

     
  • At 4:02 PM, Anonymous Anonymous said…

    Hi. I'd like to suggest a slight amendment to your post on Steven-Johnson's syndrome. I think it would be more accurate to say that SJS is caused by certain anti-viral drugs given to combat HIV, such as Nevirapine, and not by the virus itself. =)

     
  • At 6:02 PM, Blogger Rodolfo T. Rafael,M.D. said…

    Thanks for the info Ruby, I already edited my post.

    Regards

    RandyMD

     
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Name: Rodolfo T. Rafael,M.D.
Home: San Fabian, Pangasinan, Philippines
About Me: Family Physician, and Associate Professor (Medical Biochemistry, Medical Physiology and Medical Informatics)
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